Agar is a dried, hydrophilic, colloidal polysaccharide
complex extracted from the agarocytes of algae of the Rhodophyceae. The
structure is believed to be a complex range of polysaccharide chains
having alternating a-(1→3) and b-(1→4) linkages. There are three
extremes of structure noted: namely neutral agarose; pyruvated agarose
having little sulfation; and a sulfated galactan. Agar can be separated
into a natural gelling fraction, agarose, and a sulfated nongelling
fraction, agaropectin[1].
[1] 美国FDA批准药物非活性成分数据库
琼指可用作食品增稠剂、蚕丝上浆剂、缓泻剂,以及药品的胶粘剂、增稠剂和胶囊,还可作为细菌培养基、固定化酶载体、细菌的包理材料和电泳的介质。还可用于病毒,亚细胞粒子和大分子的过滤分离,以及血清抗原或抗体的观察。ADI(每日允许摄入量)不需要特殊规[1]。
Agar is widely used in food applications as a
stabilizing agent. In pharmaceutical applications, agar is used in a
handful of oral tablet and topical formulations. It has also been
investigated in a number of experimental pharmaceutical applications
including as a sustained-release agent in gels, beads, microspheres, and
tablets.It has also been reported to work as a disintegrant in
tablets.Agar has been used in a floating controlled-release tablet; the
buoyancy in part being attributed to air entrapped in the agar gel
network. It can be used as a viscosity-increasing agent in aqueous
systems. Agar can also be used as a base for nonmelting, and
nondisintegrating suppositories. Agar has an application as a suspending
agent in pharmaceutical suspensions.
Emulsifying agent; stabilizing agent; suppository base;
suspending agent; sustained-release agent; tablet binder; thickening
agent; viscosity-increasing agent[2].
[1] 以上信息来自化工字典:http://www.cnreagent.com/source/sdict.php
[2] 美国FDA批准药物非活性成分数据库